I probably should have mentioned in the first post, but he's getting it pre-built by Alienware. Obviously it won't be cost effective(I think it'll be around $2000) but, hey, it's his money. It also it means he can't customize some specific components like the heating system or PSU, both of which look okay as built though. He was looking at doing RAID possibly but I think he decided against it.
I'm primarily looking for suggestions regarding the RAM though, if someone had any insight into that it would be great. I'm not really sure how much RAM is actually needed, for instance, would 16GB actually do any good over 8GB? I can't imagine what would use 8GB of RAM.