FH2 takes more account of bullet drop, which is the distance on which fired bullets are losing height. So if you want to hit something very far away (near fog distance), especially with rifles and the like, you have to aim higher than you would do at first glance.
People post a lot about patterns and everything, but personally I haven't discovered such a thing yet. Sometimes I get a lucky hit when aiming high, sometimes I shoot several times never hitting anything. Practice this a lot with bots, that's what helps.
With scoped rifles, you have to aim even higher (or at least, it looks that way), because your target is magnified.